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Spies, Fernanda Sá; Groll, Andrea Von; Ribeiro, Andrezza Wolowski; Soares, Daniela Fernandes Ramos; Ribeiro, Marta Osório; Costa, Elis Regina Dalla; Martin, Anandi; Palomino, Juan Carlos; Rossetti, Maria Lucia; Zaha, Arnaldo; Silva, Pedro Eduardo Almeida da
(2012)
When bacteria develop drug-resistant mutations, there is often an associated biological cost; however,
some strains can exhibit low- or no-cost mutations. In the present study, a quantitative resazurin
reduction assay ...
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Ramis, Ivy Bastos; Cnockaert, Margo; Groll, Andrea Von; Mathys, Vanessa; Simon, Anne; Tortoli, Enrico; Palomino, Juan Carlos; Silva, Pedro Eduardo Almeida da; Vandamme, Peter; Andre, Emmanuel; Martin, Anandi
(2015)
Nontuberculous mycobacteria (NTM) causing human infectious disease have become increasingly common. Rapid and accurate identification to the species level is, therefore, critical. The Speed-Oligo Mycobacteria assay is an ...
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Groll, Andrea Von; Martin, Anandi; Stehr, Matthias; Singh, Mahavir; Portaels, Françoise; Silva, Pedro Eduardo Almeida da; Palomino, Juan Carlos
(2010)
Background: Multidrug resistant tuberculosis (MDR-TB) is a major threat for global tuberculosis control. The W-Beijing
Mycobacterium tuberculosis genotype has been associated with drug resistance. Elucidation of the ...
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Groll, Andrea Von; Martin, Anandi; Felix, Carolina Rodrigues; Prata, Pedro Fernandes Sanmartin; Honscha, Gunther; Portaels, Françoise; Vandamme, Peter; Silva, Pedro Eduardo Almeida da; Palomino, Juan Carlos
(2010)
RDRio is a novel Mycobacterium tuberculosis lineage of the Latin American–
Mediterranean (LAM) family. LAM has been found worldwide but is more predominant in South America. The aim of this study was to assess the presence ...
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Groll, Andrea Von; Martin, Anandi; Jureen, Pontus; Hoffner, Sven; Vandamme, Peter; Portaels, Françoise; Palomino, Juan Carlos; Silva, Pedro Almeida da
(2009)
This study evaluated cross-resistance of Mycobacterium tuberculosis strains to ofloxacin, moxifloxacin, and gatifloxacin and investigated the presence of mutations in gyrA and gyrB. Fluoroquinolone susceptibilities were ...
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Groll, Andrea Von; Martin, Anandi; Jureen, Pontus; Hoffner, Sven; Vandamme, Peter; Portaels, Françoise; Palomino, Juan Carlos; Silva, Pedro Eduardo Almeida da
(2009)
This study evaluated cross-resistance of Mycobacterium tuberculosis strains to ofloxacin, moxifloxacin, and gatifloxacin and investigated the presence of mutations in gyrA and gyrB. Fluoroquinolone susceptibilities were ...
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Groll, Andrea Von; Martin, Anandi; Portaels, Françoise; Silva, Pedro Eduardo Almeida da; Palomino, Juan Carlos
(2010)
We standardized a method to evaluate the growth kinetics of Mycobacterium tuberculosis by measuring quantitatively the reduction of resazurin by spectrophotometry. Growth curves and the rate of growth of twenty-one M. ...
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Silva, Pedro Eduardo Almeida da; Palomino, Juan Carlos
(2011)
Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared as a global emergency in 1993 by the WHO, its control is hampered by the emergence of multidrug resistance (MDR), defined as resistance ...
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Martin, Anandi; Cubillos-Ruiz, Andrés; Groll, Andrea Von; Portillo, Patricia Del; Portaels, Françoise; Palomino, Juan Carlos
(2008)
Objectives: The purpose of this study was to develop the nitrate reductase assay (NRA) for the rapid
detection of pyrazinamide resistance in Mycobacterium tuberculosis using nicotinamide resistance as
a marker of ...
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Macedo, Maíra Bidart de; Groll, Andrea Von; Fissette, Krista; Palomino, Juan Carlos; Silva, Pedro Eduardo Almeida da; Martin, Anandi
(2012)
We validated the nitrate reductase assay (NRA) for the detection of multidrug-resistant Mycobacterium
tuberculosis (MDR-TB) using sodium nitrate (NaNO3) in replacement of potassium nitrate (KNO3) as
nitrate source. NaNO3 ...
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Martin, Anandi; Groll, Andrea Von; Fissette, Krista; Palomino, Juan Carlos; Varaine, Francis; Portaels, Françoise
(2008)
The objective of this study was to evaluate the manual mycobacterium growth indicator tube (MGIT) system for the testing of Mycobacterium tuberculosis susceptibility to second-line drugs compared to the proportion
method. ...
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Neuta, Ivan Hernandez; Varela, Andres; Martin, Anandi; Groll, Andrea Von; Jureen, Pontus; Lopez, Beatriz; Imperiale, Belen; kenders, Girts; Ritacco, Viviana; Hoffner, Sven; Morcillo, Nora; Palomino, Juan Carlos; Portillo, Patricia Del
(2010)
A reverse line blot DNA hybridization format for rapid detection of multidrug-resistant tuberculosis was developed. Simultaneous detection of rifampin and isoniazid resistance in clinical isolates of Mycobacterium tuberculosis ...
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Spies, Fernanda Sá; Ribeiro, Andrezza Wolowski; Soares, Daniela Fernandes Ramos; Ribeiro, Marta Osório; Martin, Anandi; Palomino, Juan Carlos; Rossetti, Maria Lucia Rosa; Silva, Pedro Eduardo Almeida da; Zaha, Arnaldo
(2011)
Mutations related to streptomycin resistance in the rpsL and rrs genes are well known and can explain about 70% of this phenotypic resistance. Recently, the gidB gene was found to be associated with low-level streptomycin ...
